Item Type | Name |
Concept
|
Aconitate Hydratase
|
Concept
|
Acute Disease
|
Concept
|
Actins
|
Concept
|
Age Factors
|
Concept
|
Alberta
|
Concept
|
Acetylation
|
Concept
|
Administration, Inhalation
|
Concept
|
Angiotensin II
|
Concept
|
Antimycin A
|
Concept
|
Aorta, Thoracic
|
Concept
|
Arrhythmias, Cardiac
|
Concept
|
Ankle
|
Concept
|
Aftercare
|
Concept
|
Acridines
|
Concept
|
Acetylcysteine
|
Concept
|
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
|
Concept
|
Algorithms
|
Concept
|
American Heart Association
|
Concept
|
Amino Acid Oxidoreductases
|
Concept
|
Aminorex
|
Concept
|
Biology
|
Concept
|
Blood Flow Velocity
|
Concept
|
Blood Pressure
|
Concept
|
Breast Neoplasms
|
Concept
|
Aging
|
Concept
|
Ambulatory Care
|
Concept
|
Administration, Oral
|
Concept
|
Aerosols
|
Concept
|
Antineoplastic Agents
|
Concept
|
Bundle-Branch Block
|
Concept
|
Energy Intake
|
Concept
|
Carbazoles
|
Concept
|
Cardiac Output
|
Concept
|
Angiography
|
Concept
|
Animals
|
Concept
|
Animals, Newborn
|
Concept
|
Anticoagulants
|
Concept
|
Angina Pectoris
|
Concept
|
Aorta
|
Concept
|
Aminoquinolines
|
Concept
|
Quaternary Ammonium Compounds
|
Concept
|
Antihypertensive Agents
|
Concept
|
Antioxidants
|
Concept
|
Aortic Valve
|
Concept
|
Analysis of Variance
|
Concept
|
Arginine
|
Concept
|
Cyclohexanols
|
Concept
|
Aorta, Abdominal
|
Concept
|
Appetite Depressants
|
Concept
|
Benzamides
|
Concept
|
Carotid Body
|
Concept
|
Benzoates
|
Concept
|
Atropine
|
Concept
|
Dichloroacetic Acid
|
Concept
|
Digoxin
|
Concept
|
Dithionitrobenzoic Acid
|
Concept
|
Diuretics
|
Concept
|
Biotin
|
Concept
|
Body Temperature
|
Concept
|
Barium
|
Concept
|
Biopsy, Needle
|
Concept
|
Body Weight
|
Concept
|
Bone Marrow
|
Concept
|
Electrons
|
Concept
|
Capsid
|
Concept
|
Carbon Monoxide
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
Concept
|
Cardiology
|
Concept
|
Cattle
|
Concept
|
Cell Separation
|
Concept
|
Ischemic Attack, Transient
|
Concept
|
Breath Tests
|
Concept
|
Chromosomes, Human, Pair 1
|
Concept
|
Chelating Agents
|
Concept
|
Cholesterol, Dietary
|
Concept
|
Catalase
|
Concept
|
Free Radicals
|
Concept
|
Chemoreceptor Cells
|
Concept
|
Chicago
|
Concept
|
Blood Gas Analysis
|
Concept
|
Blood Pressure Determination
|
Concept
|
Bradykinin
|
Concept
|
Genetic Vectors
|
Concept
|
Chromium
|
Concept
|
Classification
|
Concept
|
Cardiotonic Agents
|
Concept
|
Connective Tissue Diseases
|
Concept
|
Creatinine
|
Concept
|
Coronary Disease
|
Concept
|
Cholesterol
|
Concept
|
Contrast Media
|
Concept
|
Coronary Artery Disease
|
Concept
|
Diabetes Mellitus, Type 2
|
Concept
|
Homozygote
|
Concept
|
Culture Media
|
Concept
|
Coronary Circulation
|
Concept
|
Immune System
|
Concept
|
Diet Surveys
|
Concept
|
Immunosuppressive Agents
|
Concept
|
Indians, North American
|
Concept
|
Injections, Intramuscular
|
Concept
|
Iron
|
Concept
|
Endothelium, Vascular
|
Concept
|
Equipment Design
|
Concept
|
Disulfides
|
Concept
|
Dithiothreitol
|
Concept
|
Cause of Death
|
Concept
|
Dogs
|
Concept
|
Echocardiography
|
Concept
|
Deferoxamine
|
Concept
|
Ductus Arteriosus, Patent
|
Concept
|
Fluoresceins
|
Concept
|
Health Surveys
|
Concept
|
Electrophysiology
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Ethers, Cyclic
|
Concept
|
Long QT Syndrome
|
Concept
|
Delivery of Health Care
|
Concept
|
Diazooxonorleucine
|
Concept
|
Chronic Disease
|
Concept
|
Clitoris
|
Concept
|
Factor VIII
|
Concept
|
Femoral Vein
|
Concept
|
Mass Screening
|
Concept
|
Cobalt
|
Concept
|
Depression
|
Concept
|
Diagnostic Imaging
|
Concept
|
Cross-Sectional Studies
|
Concept
|
Electron Transport Complex IV
|
Concept
|
Disease Susceptibility
|
Concept
|
Dobutamine
|
Concept
|
Double-Blind Method
|
Concept
|
Drug Evaluation, Preclinical
|
Concept
|
Drug Therapy, Combination
|
Concept
|
Fishes
|
Concept
|
Ferrous Compounds
|
Concept
|
Fibrinogen
|
Concept
|
Fibroblasts
|
Concept
|
Infant, Newborn
|
Concept
|
Infant, Premature
|
Concept
|
Electric Conductivity
|
Concept
|
Electrocardiography
|
Concept
|
Environment
|
Concept
|
Enzyme Activation
|
Concept
|
Methyltransferases
|
Concept
|
Microtubule-Associated Proteins
|
Concept
|
Mitral Valve
|
Concept
|
Models, Chemical
|
Concept
|
Gene Expression Regulation
|
Concept
|
Atrial Natriuretic Factor
|
Concept
|
Genes, Dominant
|
Concept
|
Fasting
|
Concept
|
Feasibility Studies
|
Concept
|
Ferric Compounds
|
Concept
|
Fetal Heart
|
Concept
|
Neovascularization, Pathologic
|
Concept
|
Nifedipine
|
Concept
|
Isoxazoles
|
Concept
|
Forced Expiratory Volume
|
Concept
|
Dietary Fats, Unsaturated
|
Concept
|
DNA (Cytosine-5-)-Methyltransferases
|
Concept
|
Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
|
Concept
|
Health Education
|
Concept
|
Heart
|
Concept
|
Cardiac Catheterization
|
Concept
|
Heart Ventricles
|
Concept
|
Dopamine
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Drug Combinations
|
Concept
|
Ductus Arteriosus
|
Concept
|
Dyspnea
|
Concept
|
Hydrogen Peroxide
|
Concept
|
Hyperlipoproteinemia Type II
|
Concept
|
Hypoglycemic Agents
|
Concept
|
Liposomes
|
Concept
|
Enzyme Induction
|
Concept
|
Herbicides
|
Concept
|
Hexokinase
|
Concept
|
Hospitalization
|
Concept
|
Fish Oils
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Inflammation
|
Concept
|
Infusions, Intravenous
|
Concept
|
Gastroesophageal Reflux
|
Concept
|
Gene Amplification
|
Concept
|
Guanylate Cyclase
|
Concept
|
Headache
|
Concept
|
Health Services Accessibility
|
Concept
|
Heart Atria
|
Concept
|
Lipoma
|
Concept
|
Luminol
|
Concept
|
Lung Diseases
|
Concept
|
Macrophages
|
Concept
|
Luminescent Measurements
|
Concept
|
Mammary Arteries
|
Concept
|
Iron-Sulfur Proteins
|
Concept
|
Ischemia
|
Concept
|
Ketanserin
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Metformin
|
Concept
|
Labor, Obstetric
|
Concept
|
Hydrolysis
|
Concept
|
Hypertension, Portal
|
Concept
|
Microfilament Proteins
|
Concept
|
Mitral Valve Stenosis
|
Concept
|
Phenylephrine
|
Concept
|
Phosphatidylcholines
|
Concept
|
Phospholipids
|
Concept
|
Pilot Projects
|
Concept
|
Myocardial Infarction
|
Concept
|
Mice, Transgenic
|
Concept
|
Minnesota
|
Concept
|
Models, Cardiovascular
|
Concept
|
Nitrates
|
Concept
|
Nitrogen Oxides
|
Concept
|
Platelet-Derived Growth Factor
|
Concept
|
Pneumonia, Viral
|
Concept
|
Meclofenamic Acid
|
Concept
|
Medical History Taking
|
Concept
|
Exercise Test
|
Concept
|
Extracellular Matrix
|
Concept
|
Immunohistochemistry
|
Concept
|
Organ Culture Techniques
|
Concept
|
Organ Size
|
Concept
|
Muscle, Smooth, Vascular
|
Concept
|
Neomycin
|
Concept
|
Glycogen
|
Concept
|
Granulomatous Disease, Chronic
|
Concept
|
Oxidative Phosphorylation
|
Concept
|
Pancreatic Elastase
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Nude
|
Concept
|
Random Allocation
|
Concept
|
Mitogens
|
Concept
|
Molecular Biology
|
Concept
|
Mutation
|
Concept
|
Myocardial Contraction
|
Concept
|
Cricetinae
|
Concept
|
Health Policy
|
Concept
|
Heartburn
|
Concept
|
Heat-Shock Proteins
|
Concept
|
Herpes Simplex
|
Concept
|
Pergolide
|
Concept
|
Ion Channels
|
Concept
|
Neutrophils
|
Concept
|
Nitric Oxide
|
Concept
|
Laparoscopy
|
Concept
|
Phagocytosis
|
Concept
|
Phosphodiesterase Inhibitors
|
Concept
|
Outpatients
|
Concept
|
Oxidation-Reduction
|
Concept
|
Oxidoreductases
|
Concept
|
Oxygen Consumption
|
Concept
|
Cholesterol, HDL
|
Concept
|
Lung Neoplasms
|
Concept
|
Rodentia
|
Concept
|
Oligopeptides
|
Concept
|
Oxygen Inhalation Therapy
|
Concept
|
Partial Pressure
|
Concept
|
Membrane Fusion
|
Concept
|
Peptides, Cyclic
|
Concept
|
Methylene Blue
|
Concept
|
Mitochondria, Heart
|
Concept
|
Persistent Fetal Circulation Syndrome
|
Concept
|
Practice Patterns, Physicians'
|
Concept
|
Phthalimides
|
Concept
|
Phenylurea Compounds
|
Concept
|
Phospholipases
|
Concept
|
Osmolar Concentration
|
Concept
|
Oxygen
|
Concept
|
Patient Care Team
|
Concept
|
Feeding Behavior
|
Concept
|
Fetus
|
Concept
|
Fibrosis
|
Concept
|
Porphyrins
|
Concept
|
Taste
|
Concept
|
Phycoerythrin
|
Concept
|
Potassium
|
Concept
|
Drug Prescriptions
|
Concept
|
Epoprostenol
|
Concept
|
Thromboembolism
|
Concept
|
Thymoma
|
Concept
|
Piperazines
|
Concept
|
Pressure
|
Concept
|
Prostaglandins
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Proto-Oncogene Proteins
|
Concept
|
Pulmonary Gas Exchange
|
Concept
|
Pulmonary Edema
|
Concept
|
Pulmonary Wedge Pressure
|
Concept
|
Pyridines
|
Concept
|
Forecasting
|
Concept
|
Glyburide
|
Concept
|
Glomerular Mesangium
|
Concept
|
Glutamine
|
Concept
|
Recurrence
|
Concept
|
Regression Analysis
|
Concept
|
Renal Circulation
|
Concept
|
Rabbits
|
Concept
|
Registries
|
Concept
|
Restaurants
|
Concept
|
Risk Factors
|
Concept
|
Vasomotor System
|
Concept
|
Pulmonary Circulation
|
Concept
|
Serotonin Antagonists
|
Concept
|
Pyrrolidines
|
Concept
|
Quality of Life
|
Concept
|
Xanthine Oxidase
|
Concept
|
Somatostatin
|
Concept
|
Rotenone
|
Concept
|
Potassium Channels
|
Concept
|
Cohort Studies
|
Concept
|
Radionuclide Angiography
|
Concept
|
Rats, Nude
|
Concept
|
Scleroderma, Systemic
|
Concept
|
Respiratory Function Tests
|
Concept
|
Interleukin-6
|
Concept
|
Spectrum Analysis
|
Concept
|
Sarcoidosis
|
Concept
|
Serotonin
|
Concept
|
Health Knowledge, Attitudes, Practice
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Swine
|
Concept
|
Thrombin
|
Concept
|
Hematologic Tests
|
Concept
|
Hemodynamics
|
Concept
|
Sheep
|
Concept
|
Silver
|
Concept
|
Societies, Medical
|
Concept
|
House Calls
|
Concept
|
Humans
|
Concept
|
Hypercapnia
|
Concept
|
Hypercholesterolemia
|
Concept
|
Hypertension, Pulmonary
|
Concept
|
Tomography, Emission-Computed, Single-Photon
|
Concept
|
Incidence
|
Concept
|
Linear Models
|
Concept
|
Single-Blind Method
|
Concept
|
Tomography, X-Ray Computed
|
Concept
|
Superoxides
|
Concept
|
Specific Pathogen-Free Organisms
|
Concept
|
Intracellular Membranes
|
Concept
|
Thrombin Time
|
Concept
|
Cardiology Service, Hospital
|
Concept
|
Ultrasonography
|
Concept
|
United States
|
Concept
|
Vasoconstriction
|
Concept
|
Stroke Volume
|
Concept
|
Oxidants
|
Concept
|
Hypertrophy, Right Ventricular
|
Concept
|
Practice Guidelines as Topic
|
Concept
|
Warfarin
|
Concept
|
Thiophenes
|
Concept
|
Genetic Variation
|
Concept
|
Vasodilator Agents
|
Concept
|
3',5'-Cyclic-GMP Phosphodiesterases
|
Concept
|
Drug Design
|
Concept
|
Calcium Channels
|
Concept
|
Sex Distribution
|
Concept
|
Isoquinolines
|
Concept
|
Echocardiography, Doppler
|
Concept
|
Lasers
|
Concept
|
Transduction, Genetic
|
Concept
|
Herpesvirus 1, Human
|
Concept
|
Hyperoxia
|
Concept
|
Proportional Hazards Models
|
Concept
|
Randomized Controlled Trials as Topic
|
Concept
|
Risk Assessment
|
Concept
|
Cell Culture Techniques
|
Concept
|
Drug Resistance, Neoplasm
|
Concept
|
Radiopharmaceuticals
|
Concept
|
Oleic Acid
|
Concept
|
Disease Management
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
rhoB GTP-Binding Protein
|
Concept
|
Uncoupling Agents
|
Concept
|
Models, Animal
|
Concept
|
Ventricular Fibrillation
|
Concept
|
S Phase
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Guanosine 5'-O-(3-Thiotriphosphate)
|
Concept
|
Ventricular Function, Left
|
Concept
|
4-Aminopyridine
|
Concept
|
Cell Adhesion Molecules
|
Concept
|
Up-Regulation
|
Concept
|
5,8,11,14-Eicosatetraynoic Acid
|
Concept
|
Extracorporeal Membrane Oxygenation
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
Concept
|
Prevalence
|
Concept
|
G1 Phase
|
Concept
|
Monocrotaline
|
Concept
|
Cardiopulmonary Resuscitation
|
Concept
|
Exercise
|
Concept
|
Fatty Acids, Omega-3
|
Concept
|
Antigens, CD
|
Concept
|
Nisoldipine
|
Concept
|
Bepridil
|
Concept
|
Lupus Erythematosus, Systemic
|
Concept
|
Mitochondria
|
Concept
|
Mitochondria, Muscle
|
Concept
|
Infusion Pumps, Implantable
|
Concept
|
Chi-Square Distribution
|
Concept
|
Comorbidity
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Rats, Wistar
|
Concept
|
Proto-Oncogene Proteins c-myc
|
Concept
|
Tacrolimus
|
Concept
|
Myocardium
|
Concept
|
Case-Control Studies
|
Concept
|
RNA Interference
|
Concept
|
Age Distribution
|
Concept
|
Methods
|
Concept
|
Genes, Reporter
|
Concept
|
Treatment Outcome
|
Concept
|
NADH Dehydrogenase
|
Concept
|
National Institutes of Health (U.S.)
|
Concept
|
Onium Compounds
|
Concept
|
Annexin A1
|
Concept
|
Guidelines as Topic
|
Concept
|
Arachidonic Acid
|
Concept
|
Cyclooxygenase Inhibitors
|
Concept
|
Gene Transfer Techniques
|
Concept
|
Tachycardia, Ventricular
|
Concept
|
Mice, Knockout
|
Concept
|
Efficiency, Organizational
|
Concept
|
Patch-Clamp Techniques
|
Concept
|
Dopamine Agonists
|
Concept
|
Cell Proliferation
|
Concept
|
Impotence, Vasculogenic
|
Concept
|
Oxidative Stress
|
Concept
|
Disease Progression
|
Concept
|
Telomerase
|
Concept
|
omega-N-Methylarginine
|
Concept
|
Cytochrome P-450 CYP2E1
|
Concept
|
Inhibitor of Apoptosis Proteins
|
Concept
|
Glucose Intolerance
|
Concept
|
Fluorodeoxyglucose F18
|
Concept
|
Simvastatin
|
Concept
|
Ventricular Remodeling
|
Concept
|
Dietary Sucrose
|
Concept
|
Bone Morphogenetic Protein Receptors, Type II
|
Concept
|
Tetraethylammonium
|
Concept
|
Calcium Signaling
|
Concept
|
Natriuretic Peptide, Brain
|
Concept
|
Mutation, Missense
|
Concept
|
Venous Thrombosis
|
Concept
|
Metabolic Syndrome
|
Concept
|
Potassium Channel Blockers
|
Concept
|
Romano-Ward Syndrome
|
Concept
|
Cross-Over Studies
|
Concept
|
Ozone
|
Concept
|
Drug Dosage Calculations
|
Concept
|
Patient Care Management
|
Concept
|
Metabolome
|
Concept
|
GTP Phosphohydrolases
|
Concept
|
Reactive Oxygen Species
|
Concept
|
Receptors, Dopamine D1
|
Concept
|
Sirtuin 3
|
Concept
|
Fatal Outcome
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
Concept
|
Gold Colloid
|
Concept
|
Myofibroblasts
|
Concept
|
Inflammasomes
|
Concept
|
Ontario
|
Concept
|
Phosphodiesterase 5 Inhibitors
|
Concept
|
Microdissection
|
Concept
|
Biomimetics
|
Concept
|
MAP Kinase Kinase 4
|
Concept
|
Positron-Emission Tomography
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Proteomics
|
Concept
|
Microarray Analysis
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
Chloride Channels
|
Concept
|
Endothelin-1
|
Concept
|
COS Cells
|
Concept
|
Microscopy, Confocal
|
Concept
|
Ryanodine Receptor Calcium Release Channel
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
Concept
|
5' Untranslated Regions
|
Concept
|
Opioid Peptides
|
Concept
|
Neovascularization, Physiologic
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
3' Untranslated Regions
|
Concept
|
Quality-Adjusted Life Years
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
Concept
|
rhoA GTP-Binding Protein
|
Concept
|
DNA, Intergenic
|
Concept
|
Tocopherols
|
Concept
|
Potassium Channels, Inwardly Rectifying
|
Concept
|
Evidence-Based Medicine
|
Concept
|
Thrombospondins
|
Concept
|
Sirolimus
|
Concept
|
Myocytes, Cardiac
|
Concept
|
Phenyl Ethers
|
Concept
|
Physical Examination
|
Concept
|
Prenatal Exposure Delayed Effects
|
Concept
|
Postoperative Complications
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Prostaglandins F
|
Concept
|
Mice
|
Concept
|
Prostaglandins, Synthetic
|
Concept
|
Pulmonary Diffusing Capacity
|
Concept
|
Pyrazoles
|
Concept
|
Pyrimidines
|
Concept
|
Pyrroles
|
Concept
|
Surveys and Questionnaires
|
Concept
|
Radionuclide Imaging
|
Concept
|
Rats, Inbred Strains
|
Concept
|
Serum Albumin
|
Concept
|
Severity of Illness Index
|
Concept
|
Research Design
|
Concept
|
RNA, Messenger
|
Concept
|
Schools, Medical
|
Concept
|
Mechanotransduction, Cellular
|
Concept
|
Substance P
|
Concept
|
Electron Transport Complex I
|
Concept
|
Sulfonamides
|
Concept
|
Angiogenesis Inducing Agents
|
Concept
|
Metabolic Equivalent
|
Concept
|
Cytokine Receptor gp130
|
Concept
|
Glucose Transporter Type 1
|
Concept
|
Rats
|
Concept
|
Nitric Oxide Synthase Type II
|
Concept
|
High-Throughput Nucleotide Sequencing
|
Concept
|
Genotyping Techniques
|
Concept
|
Real-Time Polymerase Chain Reaction
|
Concept
|
PPAR alpha
|
Concept
|
Staphylococcus aureus
|
Concept
|
Vascular Resistance
|
Concept
|
Dyslipidemias
|
Concept
|
Xanthomatosis
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
Down-Regulation
|
Concept
|
STAT2 Transcription Factor
|
Concept
|
Delayed Rectifier Potassium Channels
|
Concept
|
Multivariate Analysis
|
Concept
|
Logistic Models
|
Concept
|
Survival Analysis
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Thallium
|
Concept
|
Thyroid Neoplasms
|
Concept
|
Cyclosporine
|
Concept
|
Transfection
|
Concept
|
Trimetazidine
|
Concept
|
Ventilation-Perfusion Ratio
|
Concept
|
von Willebrand Diseases
|
Concept
|
Xanthenes
|
Concept
|
8,11,14-Eicosatrienoic Acid
|
Concept
|
Blotting, Northern
|
Concept
|
Reproducibility of Results
|
Concept
|
Patient Satisfaction
|
Concept
|
Genetic Therapy
|
Concept
|
Myocardial Reperfusion Injury
|
Concept
|
HLA-DP alpha-Chains
|
Concept
|
Lung Diseases, Interstitial
|
Concept
|
Ion-Selective Electrodes
|
Concept
|
Genome, Human
|
Concept
|
Gene Expression Regulation, Enzymologic
|
Concept
|
Survival Rate
|
Concept
|
Coronavirus Infections
|
Concept
|
Odds Ratio
|
Concept
|
Free Radical Scavengers
|
Concept
|
Ventricular Function, Right
|
Concept
|
Magnetic Resonance Imaging, Cine
|
Concept
|
Telemedicine
|
Concept
|
DNA Methylation
|
Concept
|
NADPH Oxidases
|
Concept
|
NG-Nitroarginine Methyl Ester
|
Concept
|
Echocardiography, Transesophageal
|
Concept
|
Dietary Supplements
|
Concept
|
Dexfenfluramine
|
Concept
|
Gene Silencing
|
Concept
|
Xenograft Model Antitumor Assays
|
Concept
|
Gene Targeting
|
Concept
|
Nitric Oxide Synthase
|
Concept
|
Gadolinium DTPA
|
Concept
|
Cation Transport Proteins
|
Concept
|
Hepatopulmonary Syndrome
|
Concept
|
Placental Circulation
|
Concept
|
Coronary Stenosis
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
History, 20th Century
|
Concept
|
Tubulin Modulators
|
Concept
|
E2F1 Transcription Factor
|
Concept
|
Kv Channel-Interacting Proteins
|
Concept
|
Shal Potassium Channels
|
Concept
|
Transcriptome
|
Concept
|
Nutritional Sciences
|
Concept
|
Pulmonary Disease, Chronic Obstructive
|
Concept
|
Genome-Wide Association Study
|
Concept
|
X-Ray Microtomography
|
Concept
|
AMP-Activated Protein Kinases
|
Concept
|
Ventilator-Induced Lung Injury
|
Concept
|
Dynamins
|
Concept
|
RNA, Small Interfering
|
Concept
|
Tumor Microenvironment
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Premature Birth
|
Concept
|
Actin-Related Protein 2-3 Complex
|
Concept
|
Nitric Oxide Synthase Type III
|
Concept
|
Kaplan-Meier Estimate
|
Concept
|
Latent TGF-beta Binding Proteins
|
Concept
|
Nicotinamide Phosphoribosyltransferase
|
Concept
|
rho-Associated Kinases
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 5
|
Concept
|
Growth Differentiation Factor 2
|
Concept
|
Cyclin B1
|
Concept
|
Hypolipidemic Agents
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Coronary Artery Bypass
|
Concept
|
Autopsy
|
Concept
|
Benzenesulfonates
|
Concept
|
Bronchopulmonary Dysplasia
|
Concept
|
Calcium
|
Concept
|
Calcium Channel Blockers
|
Concept
|
Canada
|
Concept
|
Cardiovascular Agents
|
Concept
|
Chromosome Aberrations
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Cyanamide
|
Concept
|
Diabetes Mellitus
|
Concept
|
Diastole
|
Concept
|
Dietary Fats
|
Concept
|
Disease Models, Animal
|
Concept
|
Electron Transport
|
Concept
|
Epinephrine
|
Concept
|
Factor VII
|
Concept
|
Fetal Hypoxia
|
Concept
|
Fibrinolytic Agents
|
Concept
|
Follow-Up Studies
|
Concept
|
Food Preferences
|
Concept
|
Food, Formulated
|
Concept
|
Genetic Counseling
|
Concept
|
Gestational Age
|
Concept
|
Glucose
|
Concept
|
Guanosine Diphosphate
|
Concept
|
Health Personnel
|
Concept
|
Heart Rate
|
Concept
|
Hernia, Diaphragmatic
|
Concept
|
Kinetics
|
Concept
|
Longitudinal Studies
|
Concept
|
Lung Diseases, Obstructive
|
Concept
|
Lymphocytes
|
Concept
|
Magnetic Resonance Imaging
|
Concept
|
Membrane Potentials
|
Concept
|
Microelectrodes
|
Concept
|
Models, Biological
|
Concept
|
Monitoring, Physiologic
|
Concept
|
Muscle Relaxation
|
Concept
|
NADH, NADPH Oxidoreductases
|
Concept
|
NADPH Dehydrogenase
|
Concept
|
Niacinamide
|
Concept
|
Norepinephrine
|
Concept
|
Panic
|
Concept
|
Phosphocreatine
|
Concept
|
Phosphoric Diester Hydrolases
|
Concept
|
Platelet Aggregation Inhibitors
|
Concept
|
Predictive Value of Tests
|
Concept
|
Prospective Studies
|
Concept
|
Pulmonary Embolism
|
Concept
|
Pyruvate Dehydrogenase Complex
|
Concept
|
Rats, Mutant Strains
|
Concept
|
Receptors, Adrenergic, beta
|
Concept
|
Receptors, Opioid
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Respiration, Artificial
|
Concept
|
Retrospective Studies
|
Concept
|
Sincalide
|
Concept
|
Syncope
|
Concept
|
Systole
|
Concept
|
Vasodilation
|
Concept
|
Vitamin A
|
Concept
|
Wisconsin
|
Concept
|
World Health Organization
|
Concept
|
Hypertriglyceridemia
|
Concept
|
Dinoprost
|
Concept
|
Thrombolytic Therapy
|
Concept
|
Gene Expression Regulation, Neoplastic
|
Concept
|
Cytokines
|
Concept
|
Databases, Factual
|
Concept
|
Iloprost
|
Concept
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
Concept
|
Okadaic Acid
|
Concept
|
Nitroarginine
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Nitric Oxide Donors
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
Calcium Channels, L-Type
|
Concept
|
Potassium Channels, Voltage-Gated
|
Concept
|
Potassium Channels, Calcium-Activated
|
Concept
|
Optic Atrophy, Autosomal Dominant
|
Concept
|
Mitochondrial Membrane Transport Proteins
|
Concept
|
MicroRNAs
|
Concept
|
Epigenesis, Genetic
|
Concept
|
Tissue Culture Techniques
|
Concept
|
Microscopy, Electron, Transmission
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channels
|
Concept
|
Kv1.5 Potassium Channel
|
Concept
|
Shab Potassium Channels
|
Concept
|
Inhibitor of Differentiation Proteins
|
Concept
|
Membrane Potential, Mitochondrial
|
Concept
|
Atrioventricular Block
|
Concept
|
G-Protein-Coupled Receptor Kinase 2
|
Concept
|
Lung Injury
|
Concept
|
HLA-DP beta-Chains
|
Academic Article
|
Superoxide dismutase: an antireductant enzyme?
|
Academic Article
|
Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue.
|
Academic Article
|
Postischemic oxygen radical production varies with duration of ischemia.
|
Academic Article
|
The non specificity of specific nitric oxide synthase inhibitors.
|
Academic Article
|
Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
|
Academic Article
|
Measurement of nitric oxide in biological models.
|
Academic Article
|
Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
|
Academic Article
|
Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis.
|
Academic Article
|
A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD.
|
Academic Article
|
Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel.
|
Academic Article
|
Diversity of response in vascular smooth muscle cells to changes in oxygen tension.
|
Academic Article
|
Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
|
Academic Article
|
Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
|
Academic Article
|
Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity.
|
Academic Article
|
Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing.
|
Academic Article
|
The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
|
Academic Article
|
Origins of breath nitric oxide in humans.
|
Academic Article
|
Ion channels in the pulmonary vasculature.
|
Academic Article
|
Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs.
|
Academic Article
|
Utility of a nitric oxide electrode for monitoring the administration of nitric oxide in biologic systems.
|
Academic Article
|
Sildenafil: from the bench to the bedside.
|
Academic Article
|
Alterations in a redox oxygen sensing mechanism in chronic hypoxia.
|
Academic Article
|
Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
|
Academic Article
|
Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
|
Academic Article
|
Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension.
|
Academic Article
|
Redox control of oxygen sensing in the rabbit ductus arteriosus.
|
Academic Article
|
Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.
|
Academic Article
|
GTP (gammaS) and GDP (betaS) as electron donors: new wine in old bottles.
|
Academic Article
|
Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
|
Academic Article
|
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
|
Academic Article
|
O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase.
|
Academic Article
|
Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
|
Academic Article
|
Coronary nitric oxide production in response to exercise and endothelium-dependent agonists.
|
Academic Article
|
Triple-bonded unsaturated fatty acids are redox active compounds.
|
Academic Article
|
Voltage-gated potassium channels in human ductus arteriosus.
|
Academic Article
|
Primary pulmonary hypertension: a vascular biology and translational research "Work in progress".
|
Academic Article
|
Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
|
Academic Article
|
The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies.
|
Academic Article
|
Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels.
|
Academic Article
|
In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
|
Academic Article
|
Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
|
Academic Article
|
Innovative strategic Canadian research training from TomorrOw's Research Cardiovascular Health Care Professionals (TORCH).
|
Academic Article
|
Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide.
|
Academic Article
|
Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.
|
Academic Article
|
The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.
|
Academic Article
|
Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
|
Academic Article
|
Acute oxygen-sensing mechanisms.
|
Academic Article
|
An evidence-based approach to the management of pulmonary arterial hypertension.
|
Academic Article
|
Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling.
|
Academic Article
|
Measurement of endothelial cytosolic calcium concentration and nitric oxide production reveals discrete mechanisms of endothelium-dependent pulmonary vasodilatation.
|
Academic Article
|
Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization.
|
Academic Article
|
Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
|
Academic Article
|
The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
|
Academic Article
|
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
|
Academic Article
|
Images in cardiovascular medicine. Untreated 37-year-old homozygous familial hypercholesterolemic smoker.
|
Academic Article
|
Association of education with dietary intake among young adults in the bi-ethnic Coronary Artery Risk Development in Young Adults (CARDIA) cohort.
|
Academic Article
|
Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.
|
Academic Article
|
The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
|
Academic Article
|
Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
|
Academic Article
|
Enhanced chemiluminescence as a measure of oxygen-derived free radical generation during ischemia and reperfusion.
|
Academic Article
|
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
|
Academic Article
|
Dilated cardiomyopathy and left bundle branch block associated with ingestion of colloidal gold and silver is reversed by British antiLewisite and vitamin E: the potential toxicity of metals used as health supplements.
|
Academic Article
|
Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
|
Academic Article
|
O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
|
Academic Article
|
Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
|
Academic Article
|
Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
|
Academic Article
|
ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
|
Academic Article
|
Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
|
Academic Article
|
Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension.
|
Academic Article
|
Cardiac EASE (Ensuring Access and Speedy Evaluation) - the impact of a single-point-of-entry multidisciplinary outpatient cardiology consultation program on wait times in Canada.
|
Academic Article
|
Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation.
|
Academic Article
|
Detection of activated O2 species in vitro and in rat lungs by chemiluminescence.
|
Academic Article
|
A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.
|
Academic Article
|
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
|
Academic Article
|
Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species.
|
Academic Article
|
The role of redox changes in oxygen sensing.
|
Academic Article
|
Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.
|
Academic Article
|
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
|
Academic Article
|
A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.
|
Academic Article
|
Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure.
|
Academic Article
|
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
|
Academic Article
|
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.
|
Academic Article
|
Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension.
|
Academic Article
|
Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
|
Academic Article
|
ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association.
|
Academic Article
|
The association between erectile dysfunction and peripheral arterial disease as determined by screening ankle-brachial index testing.
|
Academic Article
|
Hydroxylamine is a vasorelaxant and a possible intermediate in the oxidative conversion of L-arginine to nitric oxide.
|
Academic Article
|
Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
|
Academic Article
|
Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.
|
Academic Article
|
Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study.
|
Academic Article
|
Oxygen radicals and antioxidant enzymes alter pulmonary vascular reactivity in the rat lung.
|
Academic Article
|
Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
|
Academic Article
|
Lung ¹8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.
|
Academic Article
|
Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth?
|
Academic Article
|
Chronic primary and secondary thromboembolic pulmonary hypertension.
|
Academic Article
|
The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
|
Academic Article
|
Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
|
Academic Article
|
Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells.
|
Academic Article
|
Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease.
|
Academic Article
|
Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
|
Academic Article
|
Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication.
|
Academic Article
|
The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
|
Academic Article
|
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
|
Academic Article
|
Evolving epidemiology of pulmonary arterial hypertension.
|
Academic Article
|
Superoxide reduction of a disulfide: a model of intracellular redox modulation?
|
Academic Article
|
Exercise thallium testing in ventricular preexcitation.
|
Academic Article
|
Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
|
Academic Article
|
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
|
Academic Article
|
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.
|
Academic Article
|
Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
|
Academic Article
|
Redox status in the control of pulmonary vascular tone.
|
Academic Article
|
Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia.
|
Academic Article
|
Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
|
Academic Article
|
Effects of dietary fish oil on lung phospholipid fatty acid composition and intrinsic pulmonary vascular reactivity.
|
Academic Article
|
Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
|
Academic Article
|
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
|
Academic Article
|
A redox-based O2 sensor in rat pulmonary vasculature.
|
Academic Article
|
Identification of opioid receptors in the immune system using a novel combination of selective opioid ligands and indirect phycoerythrin immunofluorescence.
|
Academic Article
|
Chronic hypoxic pulmonary hypertension. Is thrombin involved?
|
Academic Article
|
Cellular and molecular basis of pulmonary arterial hypertension.
|
Academic Article
|
Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung.
|
Academic Article
|
The mitochondrion as a Swiss army knife: implications for cardiovascular disease.
|
Academic Article
|
Diversity of phenotype and function of vascular smooth muscle cells.
|
Academic Article
|
Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension.
|
Academic Article
|
NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
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Academic Article
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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Academic Article
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The measurement of NO in biological systems using chemiluminescence.
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Academic Article
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Diversity in mitochondrial function explains differences in vascular oxygen sensing.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial.
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Academic Article
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Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.
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Academic Article
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Hypoxic pulmonary vasoconstriction.
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Academic Article
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A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.
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Academic Article
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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
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Academic Article
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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
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Academic Article
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Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report.
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Academic Article
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Epigenetic mechanisms of pulmonary hypertension.
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Academic Article
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H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells.
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Academic Article
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Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks.
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Academic Article
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PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
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Academic Article
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Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment.
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Academic Article
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Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension.
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Academic Article
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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Academic Article
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Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.
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Academic Article
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The role of redox signaling in epigenetics and cardiovascular disease.
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Academic Article
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GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
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Academic Article
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Relationship between changes in dietary sucrose and high density lipoprotein cholesterol: the CARDIA study. Coronary Artery Risk Development in Young Adults.
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Academic Article
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Differences in food habits and cardiovascular disease risk factors among Native Americans with and without diabetes: the Inter-Tribal Heart Project.
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Academic Article
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Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus.
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Academic Article
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Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission.
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Academic Article
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Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
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Academic Article
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SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
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Academic Article
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Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension.
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Academic Article
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Noninvasive cardiac output measurements in patients with pulmonary hypertension.
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Academic Article
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Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
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Academic Article
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Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.
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Academic Article
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Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients.
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Academic Article
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A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.
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Academic Article
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Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
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Academic Article
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Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications.
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Academic Article
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Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension.
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Academic Article
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Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
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Academic Article
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Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
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Academic Article
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Pulmonary arterial hypertension: pathogenesis and clinical management.
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Academic Article
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Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
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Academic Article
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Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012.
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Academic Article
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Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.
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Academic Article
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Riociguat for pulmonary hypertension--a glass half full.
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Academic Article
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Mitochondrial dynamics--mitochondrial fission and fusion in human diseases.
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Academic Article
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Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
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Academic Article
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Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study.
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Academic Article
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Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
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Academic Article
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An official American Thoracic Society Statement: pulmonary hypertension phenotypes.
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Academic Article
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Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.
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Academic Article
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Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.
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Academic Article
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Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.
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Academic Article
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Mitochondrial fission and fusion in human diseases.
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Academic Article
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[Relevant issues in the pathology and pathobiology of pulmonary hypertension].
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Academic Article
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Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.
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Academic Article
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Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection.
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Academic Article
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MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
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Academic Article
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Right ventricular adaptation and failure in pulmonary arterial hypertension.
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Academic Article
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Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society.
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Academic Article
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Mitochondrial dynamics in pulmonary arterial hypertension.
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Academic Article
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Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.
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Academic Article
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Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension.
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Academic Article
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A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.
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Academic Article
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Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada.
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Academic Article
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A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension.
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Academic Article
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Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
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Academic Article
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Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again.
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Academic Article
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Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease.
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Academic Article
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Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
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Academic Article
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Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities.
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Academic Article
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Academic Article
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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
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Academic Article
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Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
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Academic Article
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Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction".
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Academic Article
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Home Virtual Visits for Outpatient Follow-Up Stroke Care: Cross-Sectional Study.
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Academic Article
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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Academic Article
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Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
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Academic Article
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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Academic Article
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An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
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Academic Article
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Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension.
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Academic Article
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Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
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Academic Article
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Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics.
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Academic Article
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Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
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Academic Article
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Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.
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Academic Article
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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
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Academic Article
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Providing care for the 99.9% during the COVID-19 pandemic: How ethics, equity, epidemiology, and cost per QALY inform healthcare policy.
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Academic Article
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Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
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Academic Article
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Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
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Academic Article
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Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes.
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Academic Article
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Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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Academic Article
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Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice.
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Academic Article
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Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer.
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Academic Article
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Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Academic Article
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Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement.
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Academic Article
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Left Main Coronary Artery Compression in Pulmonary Arterial Hypertension: Percutaneous Treatment to Improve Symptoms.
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Academic Article
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Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Academic Article
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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
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Academic Article
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Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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Academic Article
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PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
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Academic Article
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Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop.
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Academic Article
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Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.
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Academic Article
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Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility.
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Academic Article
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Mitochondria in human neutrophils mediate killing of Staphylococcus aureus.
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Academic Article
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Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
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Academic Article
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The comprehensive transcriptome of human ductus arteriosus smooth muscle cells (hDASMC).
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Academic Article
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Anomalous Right Coronary Artery Arising From Distal Left Circumflex Artery.
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Academic Article
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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
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Academic Article
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Using health administrative data to identify patients with pulmonary hypertension: A single center, proof of concept validation study in Ontario, Canada.
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Academic Article
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Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
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Academic Article
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Exertional Dyspnea and Chronotropic Incompetence Caused by Extrinsic Compression of the Right Carotid Body by a Giant Lipoma.
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Academic Article
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SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.
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Academic Article
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An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.
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Academic Article
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A Multi-omic and Multi-Species Analysis of Right Ventricular Failure.
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Academic Article
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Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension.
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Academic Article
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Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension.
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Concept
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Imatinib Mesylate
|
Concept
|
Sildenafil Citrate
|
Concept
|
Ranolazine
|
Concept
|
Venlafaxine Hydrochloride
|
Concept
|
Health Equity
|
Concept
|
Forkhead Box Protein O1
|
Concept
|
NLR Family, Pyrin Domain-Containing 3 Protein
|
Concept
|
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
|
Concept
|
Soluble Guanylyl Cyclase
|
Concept
|
Betacoronavirus
|
Concept
|
NADPH Oxidase 2
|
Concept
|
DNA (Cytosine-5-)-Methyltransferase 1
|
Concept
|
Mitochondrial Dynamics
|
Concept
|
RNA, Long Noncoding
|
Concept
|
Hernias, Diaphragmatic, Congenital
|
Concept
|
Calcineurin Inhibitors
|
Concept
|
Endothelin Receptor Antagonists
|
Concept
|
Familial Primary Pulmonary Hypertension
|
Concept
|
ErbB Receptors
|
Concept
|
Vascular Remodeling
|
Grant
|
Impaired mitochondrial fusion in pulmonary arterial hypertension
|
Grant
|
O2 sensing in the human and rabbit ductus arteriosus.
|
Grant
|
EDRF IN NORMAL AND HYPERTENSIVE PULMONARY VASCULATURE
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Grant
|
The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
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Academic Article
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Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting.
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Academic Article
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Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response.
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Academic Article
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Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus.
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Academic Article
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The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases.
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Academic Article
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Multi-omic and multispecies analysis of right ventricular dysfunction.
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Academic Article
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The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases.
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Academic Article
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Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions.
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Academic Article
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The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
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Academic Article
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Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.
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Academic Article
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Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension.
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Academic Article
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Pulmonary hypertension.
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Academic Article
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Germline and Somatic Mutations in DNA Methyltransferase 3A (DNMT3A) Predispose to Pulmonary Arterial Hypertension (PAH) in Humans and Mice: Implications for Associated PAH.
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